Ursolic Acid Powder Product Introduction
Ursolic Acid Powder, produced by Baoji Hancuikang Bio-Technology Co., Ltd, is a natural compound extracted from plants.it is a white or light yellow powder with various health benefits.
Ursolic Acid (UA)
Aliases: Ursonic acid
CAS No.: 77-52-1
Molecular Formula: C₃₀H₄₈O₃, Molecular Weight: 456.7
Chemical Classification: Pentacyclic triterpenoid
1. Physical and Chemical Properties
Appearance: White, lustrous prismatic crystals for high purity; brownish-yellow powder for low purity.
Melting Point: 283–288℃ (decomposes)
Specific Rotation: [α]D²⁵ +67.5° (c=1, alcoholic KOH solution)
Solubility: Insoluble in water; soluble in methanol, acetone, pyridine, and hot ethanol; slightly soluble in cold ethanol and ether; soluble in hot DMSO (>25 mg/mL).
Stability: Stable at room temperature and protected from light; relatively stable to acids, forms salts with strong bases.
Specifications
| Appearance | White or light yellow powder |
|---|---|
| Purity | 25%-98% |
| Loss on Drying | ≤1.0% |
Product Function
III. Core Pharmacological Activities (Validated)
Antitumor: Inhibits tumor cell proliferation, induces apoptosis, and suppresses angiogenesis; effective against liver, lung, breast, colon, and other cancers.
Anti-inflammatory: Inhibits COX-2, NF-κB, and MAPK pathways; alleviates acute and chronic inflammation (e.g., arthritis, dermatitis).
Antioxidant: Scavenges free radicals and enhances SOD and CAT activities; anti-aging, skin-protective, and improves liver injury.
Metabolic regulation: Reduces blood lipids and glucose, improves insulin resistance; inhibits fatty liver and alleviates obesity-related metabolic disorders.
Hepatoprotective: Resists liver fibrosis and promotes hepatocyte regeneration; adjunctive therapy for viral hepatitis.
Antibacterial / Antiviral: Inhibits Staphylococcus aureus and Escherichia coli; active against hepatitis B and herpes viruses.
Neuroprotective: Improves cognition, exerts antidepressant effects, and mitigates brain aging damage.
Muscle-protective: Increases muscle mass, enhances strength, prevents muscle atrophy, and relieves fatigue.
IV. Applications
1. Pharmaceuticals
Lipid-lowering agents: Glossy privet leaf extract capsules (Class II new drug in China) for primary hyperlipidemia.
Liver support: Adjunctive treatment for chronic hepatitis and liver fibrosis.
Antitumor research: Serves as a lead compound for developing low-toxic anticancer drugs.
Anti-inflammatory preparations: Topical ointments for dermatitis and acne; oral formulations for arthritis relief.
2. Cosmetics (Popular)
Benefits: Whitening, anti-inflammatory, antioxidant, anti-aging, oil control, anti-acne.
Applications: Creams, serums, lotions, sunscreens, anti-acne products; often combined with niacinamide and retinol.
3. Food & Health Products
Functions: Antioxidant, immune-enhancing, metabolic-regulating, hepatoprotective.
Forms: Dietary supplements, functional beverages, plant extract additives.
V. Safety & Limitations
Toxicity: Low toxicity; LD50 >5000 mg/kg (oral, rats); safe for long-term low-dose use.
Drawbacks: Very poor water solubility (<1 μg/mL) and low oral bioavailability (<5%), limiting clinical application.
Improvements: Formulated as nanoparticles, liposomes, cyclodextrin inclusion complexes, or structurally modified to enhance solubility and bioavailability.
VI. Extraction & Preparation
Natural Extraction
Raw materials: Glossy privet leaves, loquat leaves, rosemary, etc.
Process: Ethanol reflux extraction → concentration → defatting → recrystallization (ethanol/acetone) → drying (purity: 90%–98%).
Biosynthesis
Synthesized via the mevalonate pathway using engineered yeast/E. coli (under development, low yield).
In outline, Ursolic Corrosive Powder's adaptable applications range across drugs, beauty care products, food-added substances, and horticulture, attributable to its potential medical advantages and properties. Its capacity to address different well-being and agrarian necessities features its significance in these assorted enterprises. Further innovative work in every one of these areas might uncover many more applications and advantages of this normal compound.
OEM Service
Baoji Hancuikang Bio-Technology Co., Ltd provides OEM services, allowing customers to customize packaging, labeling, and formulation. We have a large inventory of rosemary extract ursolic acid, ensuring prompt delivery to meet your demands. guarantees high-quality products, and we also support testing of our products to maintain their purity and quality.
For any further inquiries or if you are interested in purchasing ursolic acid powder, please feel free to contact Baoji Hancuikang Bio-Technology Co., Ltd. We are a professional manufacturer and supplier, with a large inventory, complete certifications, fast delivery, and supportive OEM services. We ensure secure packaging and provide testing support. Contact us today to choose your own ursolic acid powder!You can contact us by e-mail: fxu45118@gmail.com or Whatsapp/Wechat:86-13379475662.
